Mechanism of action of 2-mercapto-1(beta-4-pyridethyl)benzimidazole: a reversible inhibitor of interferon activity.
نویسندگان
چکیده
2-mercapto-1(beta-4-pyridethyl)benzimidazole (MPB) inhibited the development of antiviral activity induced by interferon in chick cells. The MPB effect was reversed by washing the cells. The action of MPB was on a step immediately following interferon binding but before the cellular RNA and protein synthesis that appear to be required for interferon action. The step blocked by MPB possibly involves cellular phospholipid synthesis.
منابع مشابه
Studies on the Mechanism of Interferon Action
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 65 1 شماره
صفحات -
تاریخ انتشار 1970